Certain portions of the genome are more likely to mutate than others; thus, the randomness is not evenly distributed. 1 This makes it much more difficult for evolution because for a low-mutation portion of the genome to evolve, evolution must constantly weed out the much more common mutations in other portions of the genome.
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Sanford, J. C., & Baumgardner, J. (2008). Genetic Entropy & the Mystery of the Genome (3rd ed.). Waterloo, NY: FMS Publications.
- Sanford, 2008, p. 138 ↩